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N-丁二酸,S-乙酰基巯基乙二醇酯:LM810212 C

SATA

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N-丁二酸,S-乙酰基巯基乙二醇酯

英文名SATA
别名SATA
相关类别蛋白质化学修饰试剂储存冷冻(-20℃) 避光+干燥
分子量231.23

产品描述

概述

SATA is the reagentfor introducing protected sulfhydryls into proteins, peptides and other molecules. They are the N-hydroxysuccinimide (NHS) esters of S-acetylthioacetic and propionic acid. A stable, covalent amide bond is formed from the reaction of the NHS ester with primary amines. The amine reacts with the NHS ester by nucleophilic attack, with N-hydroxysuccinimide being released as a by-product. Deprotection (deacylation) to generate a sulfhydryl for use in cross-linking and other applications is accomplished using hydroxylamine HCl.

特点


  • Reaction conditions are mild and non-denaturing;The reaction is specific toward primary amines;Sulfhydryl groups are introduced in a protected form, allowing the modified molecule to be stored indefinitely and then later treated with hydroxylamine to expose the labile sulfhydryl group for final conjugation reactions.


应用

Soluble in DMSO

组份

100 mg/bottle

技术规格

Molecular Weight231.23
Spacer Arm Length2.8
Purity>95% on TLC
Reactive groupsNHS ester and thioacetyl protected sulfhydryl

本产品只适用于科研,不能用于临床诊断。严禁用于临床医疗及其他非科研用途!


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