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Quercetin Dihydrate CAS:6151-25-3 LM8260PIN

Quercetin dihydrate 是一种黄酮类天然产物,可激活或抑制许多蛋白质的活性。它可激活SIRT1,也可抑制PI3K,抑制 PI3K γ、PI3K δ和PI3K β 的IC50值分别为 2

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Quercetin Dihydrate

产品描述

Quercetin is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effects.

PRODUCT INFORMATION

Chemical Name: Quercetin Dihydrate

Cat. Number: LM8260PIN

CAS Number: 6151-25-3 

Chemical Structure:

2023060410393017976

体外活性

Quercetin, a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. The pharmacological activities of quercetin that modulate antioxidation/oxidation/kinase-signaling pathways might be differentially elicited in neurons compared with malignant cells, ultimately promoting cell survival or death in a cell type- and metabolism-specific manner. Whereas the broad antioxidation and anti-inflammatory activities of quercetin are important for neuronal survival, the oxidative, kinase- and cell cycle-inhibitory, apoptosis-inducing effects of quercetin are essential for its anticancer effects. [1]

体内活性

LD50: Mice 159 mg/kg (i.g.) [2]

分子式

C15H14O9

分子量

338.268

别名

槲皮素;Sophoretin;Quercetin Dihydrate

储存和溶解度

H2O:<1 mg/mL

Ethanol:15 mg/mL(44.3 mM)

DMSO:62 mg/mL (183.3 mM)

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

本产品只适用于科研,不能用于临床诊断。严禁用于临床医疗及其他非科研用途!

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