Suramin Sodium Salt
产品描述
Suramin Sodium is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis.
PRODUCT INFORMATION
Chemical Name: Suramin Sodium Salt
Cat. Number: LM8005DIN
CAS Number: 129-46-4
PHYSICAL AND CHEMICAL PROPERTIES
Molecular Formula: C51H34N6Na6O23S6
Molecular Weight: 1429.15
Appearance: Soild
Storage: Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Chemical Structure:
ANALYTICAL DATA
HPLC:Consistent with structure
HNMR:Consistent with structure
Purity:97.47%
Conclusion:The test result is consistent with structure
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